Testosterone and
Cancer and Cancer Increase
Copyright 2005, James Michael Howard,
I suggest the pattern of cancer incidence reported by Hall,
et al., (Urbanization and Breast Cancer Incidence in North Carolina, 1995-1999;
Ann Epidemiol. 2005 May 25), that breast cancer may be higher in urban counties
and that "These results suggest that there are urban effects that
influence the incidence of lung cancer that are not explained entirely by
smoking behaviour." (Soc Sci Med. 2005 Jun;60(12):2833-43.
Epub 2005 Jan 21) may
be explained by testosterone levels. It
is my hypothesis (1994) that high testosterone is involved in initiation of
female breast cancer, as well as other cancers, male and female, (Annals of
Internal Medicine 2005; 142: 471-2). A
report comparing rural areas and a large city found that testosterone is higher
in the large city (Folia Histochem Cytobiol. 2001;39
Suppl 2:38-9).
I suggest the pattern of cancer incidence reported in the
article may be due to the effects of higher levels of testosterone in urban
populations. Also, it is my hypothesis
that the "secular trend," the increase in size and earlier puberty in
children is caused by an increase in the percentage of individuals of higher
testosterone within populations with time.
Therefore, as this percentage increases with time, cancer also
increases.